Healthy Aging

Proof-of-Principle 2021

Brain Health | Diet and Nutrition

Deadline: August 31, 2021

This funding opportunity will provide research grants of up to $300,000 over a maximum of 24 months to support high-impact projects that pursue translational or interventional research regarding the microbiome’s influence on brain health, or via the interactions between diet, nutrition, and the microbiome.

Please refer to the Program Details and Request for Applications (RFA) for more information and details on how to apply.

Program Overview

Goal: To provide funding to innovative projects that seek to leverage the microbiome to deliver new translational interventions or preventative strategies for improving health. This includes modifying, manipulating, or exploiting the microbiome to confer immune benefits or treat diseases, with a focus on brain health and diet & nutrition.

Funding: Up to $300,000 per project over up to 24 months. The Foundation will commit up to ~ $3,000,000 to projects selected through this program (approximately 10 projects).

Project Eligibility:

  • Develop a new microbiome intervention or preventative strategy for improving brain health; OR
  • Leverage the microbiome to maximize the benefits of diet and nutrition.
  • Full definitions can be found in the Program Details document.

Application Process

  1. Confirm intent to apply by emailing
  2. Submit a completed Letter of Intent (see template below) via

Important dates

Information Webinar: August 3, 2021 (register here) & August 5, 2021 (register here) @ 3:00pm ET
LOI deadline: August 31, 2021 @ 2:00pm ET
Proposal deadline: October 22, 2021 @ 2:00 pm ET
Anticipated award announcement: December 2021