The Proof of Principle program supports Canadian research efforts on the human microbiome. The objective of this program is to fund Canadian scientists performing high-risk, high-reward translational research that leverages the microbiome towards improving human health.
The program is split into two funding approaches: Microbiome Mechanisms and Lifestyle Approaches, as outlined below:
Microbiome Mechanisms
This funding opportunity will provide research grants to support high-impact projects that seek to improve our understanding of the relationship between the microbiome and health towards future applications.
Eligible projects include the following:
- Significantly expand mechanistic understanding of the microbiome in influencing physiology, health and disease.
- Provide new insights that lead toward novel or improved applications of the microbiome to improving health.
Lifestyle Approaches
This funding opportunity will provide research grants to support high-impact projects that seek to leverage the microbiome to improve health.
Eligible projects include the following:
- Establish an innovative line of translational or implementation research and provide proof-of-principle evidence in support of new health applications.
- Work towards a recommendation, intervention or preventative strategy that improves health by leveraging the microbiome.
- Focus on eligible research surrounding the application of lifestyle approaches in microbiome health.
For information about the Proof-of-Principle program, see our Grant Calls.